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How Saccharomyces boulardii Works:   Saccharomyces boulardii is a nonpathogenic yeast strain that, when lyophilized, readily colonizes the gut and resists bile salts (which is crucial since it needs to get past some very harsh digestion). In contrast to bacteria, which comprise more than 99% of human flora, yeast accounts for less than 1%. Nonetheless, Saccharomyces boulardii is a particularly beneficial yeast (and it’s antibiotic-resistant, unlike bacteria).

Moreover, a contemporary meta-analysis suggests that Saccharomyces boulardii supports gastrointestinal integrity by promoting healthy inflammatory responses in the intestines and colon of humans