CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor. CSV0C018875 exhibits lesser cytotoxicity than BIX-01294.

Product information

CAS Number: 442150-41-6

Molecular Weight: 312.79

Formula: C18H17ClN2O

Chemical Name: 6-chloro-N-(4-ethoxyphenyl)-2-methylquinolin-4-amine

Smiles: CC1=CC(NC2C=CC(=CC=2)OCC)=C2C=C(Cl)C=CC2=N1

InChiKey: NQNAQPVPGUVZAF-UHFFFAOYSA-N

InChi: InChI=1S/C18H17ClN2O/c1-3-22-15-7-5-14(6-8-15)21-18-10-12(2)20-17-9-4-13(19)11-16(17)18/h4-11H,3H2,1-2H3,(H,20,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CSV0C018875 (2.5-20 μM; 48 hours) inhibits the levels of H3K9me2 modifications in the histones.

Products are for research use only. Not for human use.