Reelin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91164-50, BS91164-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P78509(Human) P58751(Rat)

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200

Background: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in "reeler" mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1 in a signaling pathway that controls cell positioning in the developing brain and is also thought to be a direct effector of the neurotrophin BDNF.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Reelin polyclonal antibody detects endogenous levels of Reelin protein.

Bioworld Molecular Weight: 388 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Reelin antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-Reelin antibody. Counter stained with hematoxylin.

Alternative Name: RELN, LIS2, PRO1598, Reeler, Reelin, RELN, RELN, RL,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified